Milwaukee Brewers' Kolten Wong sliding into home

Milwaukee Brewers’ Kolten Wong slides to score against the Chicago Cubs during the seventh inning of a baseball game, Thursday, April 7, 2022, in Chicago. (AP Photo/Kamil Krzaczynski)

  • The Brewers are -165 road favorites over the Cubs on Friday
  • Brandon Woodruff (9-10, 2.56 in 2021) will start for the Brewers against Justin Steele (4-4, 4.26)
  • A look at the Brewers vs Cubs odds and matchup can be found below with a pick

The Chicago Cubs will look to build on their opening day victory when they host the Milwaukee Brewers at 2:20 p.m. ET Friday at Wrigley Field.

The Cubs edged the Brewers 5-4 on Thursday to open a four-game series. Ian Happ had three hits, including the tiebreaking double, to lead Chicago.

Brewers vs Cubs Odds

Team Moneyline Runline Total
Milwaukee Brewers -165 OFF OFF
Chicago Cubs +138 OFF OFF

Odds as of April 7th at Barstool Sportsbook.


Brandon Woodruff (9-10, 2.56 in 2021) is scheduled to start for the Brewers against Justin Steele (4-4, 4.26).

The Brewers have an implied win probability of 62.26% as -165 favorites. The start of the game could be delayed as there is an 80% chance of rain with an expected high temperature of just 41 degrees and a west wind from 10-15 mph.

Woodruff vs Steele

9-10 Record 4-4
2.56 ERA 4.26
3.30 xERA 4.04
0.96 WHIP 1.35
4.91 SO/W 2.19

Brewers Betting Outlook

Woodruff will make his first start of the season after a shaky spring training performance. He was rocked for 15 runs (14 earned) and 16 hits in 11.2 innings in the Cactus League with 12 strikeouts and four walks.

That came after Woodruff was selected to the last two All-Star Games.

In 13 career games (11 starts) against the Cubs, Woodruff is 2-1 with a 2.73 ERA. He is 1-1 with a 1.98 ERA in seven games (five starts) at Wrigley Field.

Few Cubs hitters have a good history against Woodruff. Happ is 3 for 21 (.143) with a home run but seven strikeouts while Jason Heyward is 3 for 20 (.150).

Andrew McCutchen, Willy Adames and Rowdy Tellez each had two hits Thursday for the Brewers and Lorenzo Cain drove in two runs.

Cubs Betting Preview

Happ’s two-run double in the seventh inning Thursday snapped a 3-3 tie and proved to be the game-winning hit.

Nico Hoerner hit the first home run of the major league season. Japanese outfielder Seiya Suzuki reached base three times and scored in his MLB debut.

Steele struggled with his control this spring as he issued seven walks in 6.2 innings. However, he also allowed just two runs and three hits while striking out five.

In his rookie year in 2021, Steele was 0-1 against the Brewers with a 3.97 ERA in four games (two starts). He struggled at home, though, going 2-3 with a 6.07 ERA in 10 games (five starts).

Steele has had his way with Brewers leadoff man Kolten Wong, holding him hitless in six at-bats.

Brewers vs Cubs Injury Report

Brewers third baseman Luis Urias (quad) is on the 10-day injured list. Backup catcher Pedro Severino was suspended 80 days by MLB this week for testing positive for a performance enhancing drub.

The Cubs are without shortstop Andrelton Simmons (shoulder), who is on the 10-day IL.

Brewers vs Cubs Last 10 Meetings

Date Home Team Away Team Score
4/7/22 Cubs Brewers CHC, 5-4
9/19/21 Brewers Cubs CHC, 6-4
9/18/21 Brewers Cubs MIL, 6-4
9/17/21 Brewers Cubs MIL, 8-5
8/12/21 Cubs Brewers MIL, 17-4
8/11/21 Cubs Brewers MIL, 10-0
8/10/21 (2) Cubs Brewers MIL, 6-3
8/10/21 (1) Cubs Brewers MIL, 4-2
6/30/21 Brewers Cubs MIL, 15-7
6/29/21 Brewers Cubs MIL, 2-1

Brewers vs Cubs Prediction

Thursday’s result was the reversal from last season when the Brewers won 15 of 19 games against the Cubs. Urias led Milwaukee by hitting .356 (21 for 59) with seven doubles, five home runs, 23 RBIs and 10 walks.
Woodruff had a difficult exhibition season but one of the more meaningless things in sports is spring training stats. He always pitches well in Wrigley Field and that will continue

The Pick: Brewers ML (-165)

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John Perrotto

Sports Writer


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