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Kentucky Wildcats quarterback Devin Leary throws a pass

Sep 2, 2023; Lexington, Kentucky, USA; Kentucky Wildcats quarterback Devin Leary (13) throws a pass during the first quarter against the Ball State Cardinals at Kroger Field. Mandatory Credit: Jordan Prather-USA TODAY Sports

  • Kentucky vs Eastern Kentucky goes down Saturday night in College Football Week 2
  • The Wildcats are favored by 31 points over the Colonels at Kroger Field in Lexington, KY
  • Read below for Kentucky vs Eastern Kentucky odds, spread and predictions for CFB Week 2

The latest Kentucky vs Eastern Kentucky odds suggest the Wildcats will cruise to victory over their in-state rivals in College Football Week 2. Mark Stoops’ team is favored by 31.5 points over the Colonels at Kroger Field.

Kentucky started their season with a blowout win over Ball State, while Eastern Kentucky was on the receiving end of a blowout victory by Cincinnati. This will be the first meeting between the two Bluegrass programs since 2017.

Let’s dive into the Kentucky vs Eastern Kentucky odds and offer our prediction for this Saturday night CFB clash.

Kentucky vs Eastern Kentucky Odds

Team Spread Moneyline Total
Kentucky Wildcats -31.5 (-110) OFF Over 56 (-110)
Eastern Kentucky Colonels +31.5 (-110) OFF Under 56 (-110)

In the Kentucky vs Eastern Kentucky odds, the Wildcats are 31.5-point favorites, while the over/under is listed at 56 points.

Kickoff for Kentucky vs EKU is 3:00 PM EST, with the game being streamed on SEC Network Plus & ESPN Plus. The match will not be televised.


Odds as of September 7, 2023. Check out Kentucky Sports Betting Apps to unlock bonus money ahead of the official launch on September 28th. 

Wildcats Roar Past Cardinals

Kentucky began its 2023 college football season with a commanding 44-14 victory over Ball State in Week 1. Mark Stoops’ team Entered the game as 25-point favorites and had no issues covering the spread against an inferior opponent.

Running back Ray Davis, the Vanderbilt transfer, was the star of the show in Week 1. He rushed for 112 yards, including a 30-yard touchdown sprint that sealed the game. QB Devin Leary, another debutant, threw for 241 yards and a TD, proving his mettle after a career at North Carolina State.

Defensively, the Wildcats’ defense was a force to be reckoned with. They posted eight tackles for loss, three sacks, and even stopped the Cardinals at the goal line in the fourth quarter. This was a unit that was not to be messed with.

Kicker Alex Raynor also made his Kentucky debut memorable, nailing three field goals from at least 40 yards out. His performance was the icing on the cake in a game where Kentucky outclassed Ball State in all facets.

Colonels Blown Out by Bearcats

Eastern Kentucky kicked off their 2023 CFB campaign with an ugly 66-13 loss to the Cincinnati Bearcats on Saturday. New Cincy quarterback Emory Jones had a field day, completing 19 of 23 passes for 345 yards and seven touchdowns.

Colonels quarterback Parker McKinney completed 13 of 24 passes for 177 yards and one TD along with two interceptions. The Eastern Kentucky run game did at least find some success, rushing for 125 yards against the UC defense, including 68 yards from RB Joshua Carter.

Kentucky vs Eastern Kentucky Prediction

These two teams played a 27-16 nail-biter back in 2017, but we don’t see the 2023 rematch playing out in a similar fashion. The EKU secondary got torched in their Week 1 opener and now they face a QB who has thrown for over 7,000 yards in his collegiate career.

Here are some key betting trends to note for Kentucky vs EKU:

  • Eastern Kentucky are 0-5 SU in their last 5 games when playing on the road against Kentucky
  • Kentucky are 11-2 ATS in their last 13 games played in Week 2
  • The total has gone UNDER in 9 of Kentucky’s last 10 games

Leary will improve in his second game in this new offense, and Ray Davis should once again be a force on the ground. Our best bet for this Kentucky vs Eastern Kentucky clash is to take the Wildcats to cover the 35 points.

  • Pick: Kentucky Wildcats -35 (-110)


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Brady Trettenero

Lead NHL & NCAAF Editor


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