Opening Bills vs Broncos Odds, Spread, Total for Divisional Round

• The Buffalo Bills and Denver Broncos will meet at Mile High in the NFL Divisional Round
• The Bills/Broncos odds project a razor-thin margin
• See the opening Bills vs Broncos odds, including spread, moneyline, and game total, for the 2026 playoffs

After a wild back-and-forth victory over Jacksonville, the #6 Buffalo Bills (13-5, 6-3 away) have advanced to the Divisional Round of the NFL playoffs, where they will meet the top-seeded Denver Broncos (14-3, 8-1 home). Despite Denver getting the week to rest and having home-field advantage, the Broncos have opened as a slight home underdog.

The Bills and Broncos will meet on either Saturday, Jan 17th, or Sunday, Jan 18th, with a spot in the AFC Championship Game on the line.

Opening BUF Bills vs DEN Broncos Odds & Spread

The spread has opened at BUF -1.5 with the Bills a -126 favorite on the moneyline. The Broncos come back as modest +108 home underdogs. The game total is sitting at 47.5 with the under slightly favored at -115.

Odds as of 11:15 pm ET at FanDuel. Lock in the top Super Bowl betting promos for the 2026 playoffs.

BUF vs DEN Statistical Comparison