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- The NFC matchups have already been set: 49ers vs Seahawks, Rams vs Bears
- The Bears are home underdogs for the second straight week
- See the opening Divisional Round odds for all games on the board so far
The 2026 NFL Divisional Round will take place next Saturday and Sunday (Jan. 17-18) and the first matchups have been set. The NFC #1 Seattle Seahawks will host the #6 San Francisco 49ers in an all-NFC West tilt, while the #2 Chicago Bears will welcome the #5 Los Angeles Rams to Soldier Field.
The AFC matchups are still TBD. The #1 Denver Broncos will host the worst remaining seed, while the #6 Buffalo Bills will be on the road against one of #2 New England, #4 Pittsburgh, or #5 Houston.
The table below lists the opening Divisional Round odds for all cemented matchups. The others will be added as the second round of NFL playoff bracket is determined.
NFL Divisional Round Odds
The opening lines favor the one home team and one road team with the totals differing by a full four points.
Odds as of 7:43 pm ET at FanDuel Sportsbook.
Odds as of Jan. 11 at DraftKings. Lock in the top NFL betting promos for the 2026 playoffs.
Seattle Opens as Big Favorite Over San Francisco
The 49ers dethroned the champion Eagles in Philadelphia on Sunday, earning a 23-19 road win as six-point underdogs. Next week, they’ll be staring down an even bigger spread, at least if the opening lines hold. The Niners are currently seven-point road underdogs at Seattle in the teams’ third meeting of the season.
San Francisco beat the Seahawks 17-13 in Seattle, but that was all the way back in Week 1. The Seahawks took a 13-3 decision in Week 18 in the Bay Area.
Bears Home Underdogs … Again
The Bears looked dead in the water when they fell behind Green Bay 21-6 in the Wild Card Round. But a furious fourth-quarter comeback by Caleb Williams and company led Chicago to a thrilling 31-28 victory as 1.5-point home underdogs.
Next weekend, they’ll host the Rams as even bigger ‘dogs, currently catching 4.5 points in the opening odds for the Divisional Round.
Bookmark SBD’s NFL odds page to see up-to-the-minute lines for every 2026 playoff game.